Human Recombinant IGF-1

Insulin-Like Growth Factor-1

Human recombinant protein from the MegaProt line, developed for studies of growth, cell survival, proliferation, and functional maintenance in advanced cellular models.

IGF-1 MegaProt is currently in Beta validation stage. The technical information presented is referential and may be updated as characterization, stability, biological activity, and functional validation assays progress. For updated information regarding availability, format, and conditions of use, please contact us directly.

Beta Stage

Human Origin

Functional Studies

Request Information
Biological Source Human

Content
Expressed in a human Megakaryoblastic cell line
Format
Lyophilized
Molecular Weight
~14 kDa monomer / ~28 kDa dimer
Storage Conditions
Once reconstituted, aliquot and store at -80°C until use
Suggested Application
Cell culture
Storage Temperature
-20°C a -80°C

General Description

IGF-1 is a growth factor associated with proliferation, cell survival, and anabolic metabolism. In cell culture, it is used to support expansion, viability, and functional maintenance of different cellular models, especially under conditions that require greater medium control and defined growth support.

Biological Action

IGF-1 acts mainly through the IGF1R receptor, activating pathways associated with survival, proliferation, and cell growth. Its signaling can promote cell cycle entry, reduce apoptosis, and support differentiation processes when combined with other factors in the medium.

Usage Considerations

The use of IGF-1 requires careful definition of the cell type, culture status, concentration, exposure time, and presence of other factors. Due to its context-dependent effect, dose-response curves and markers of proliferation, viability, apoptosis, or differentiation should be evaluated according to the study objective.

WHAT IS IT USED FOR?

IGF-1 recombinant human can be evaluated in studies aimed at cell survival, growth, and functional response in culture. Its use will depend on the cell model, experimental conditions, and the objectives of each investigation.
Cell Survival

Support in models where the goal is to reduce apoptosis and maintain viability during critical culture stages.
Cell Proliferation

Stimulation of cell growth and expansion in primary cultures, established cell lines, and specialized models.
Assisted Differentiation

Use as a cofactor in protocols where other stimuli drive cell differentiation programs.
Regenerative Models

Application in systems focused on specialized matrix, tissue repair, and cellular response studies.

REQUEST YOUR SAMPLE

Tell us about your experimental model and we will guide you on availability, conditions of use, and evaluation of IGF-1 MegaProt.

1

Contact Us

Complete the Beta sample request form.

2

Evaluation

We review your research profile and intended use.

3

Delivery

We ship the sample with an included usage protocol.

4

Feedback

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