Human Recombinant PDGF-B

Platelet-Derived Growth Factor B

Human recombinant protein from the MegaProt line, developed for studies of proliferation, cell migration, angiogenesis, tissue remodeling, and in vitro repair models.

PDGF-B MegaProt is currently in Beta validation stage. The technical information presented is referential and may be updated as characterization, stability, biological activity, and functional validation assays progress. For updated information regarding availability, format, and conditions of use, please contact us directly.

Beta Stage

Human Origin

Functional Studies

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Biological Source Human

Content
Expressed in a human Megakaryoblastic cell line
Format
Lyophilized
Molecular Weight
~14 kDa monomer / ~28 kDa dimer
Storage Conditions
Once reconstituted, aliquot and store at -80°C until use
Suggested Application
Cell culture
Storage Temperature
-20°C a -80°C

General Description

PDGF-B is a platelet-derived growth factor associated with proliferation, migration, and cellular remodeling. In cell culture, it is primarily used to study responses in mesenchymal cells, fibroblasts, osteoblasts, pericytes, and other models related to tissue repair, angiogenesis, and extracellular matrix dynamics.

Biological Action

PDGF-B acts through PDGFR receptors, activating pathways associated with proliferation, survival, migration, and extracellular matrix synthesis. Its signaling can support the recruitment of mesenchymal cells, expansion of fibroblasts or osteoblasts, and processes related to wound healing, angiogenesis, and tissue regeneration.

Usage Considerations

The use of PDGF-B requires careful definition of the cell type, experimental objective, concentration, exposure time, and mode of presentation. Due to its effects on proliferation and migration, specific readouts such as viability, cell migration, extracellular matrix expression, differentiation, or response in in vitro repair systems should be evaluated.

WHAT IS IT USED FOR?

PDGF-B recombinant human can be evaluated in studies aimed at proliferation, migration, and cellular remodeling. Its application will depend on the experimental model, culture conditions, and the objectives of each investigation.
Cell Migration

Evaluation of chemotaxis, cell displacement, and recruitment in defined experimental models.
Tissue Repair

Application in wound healing studies, extracellular matrix remodeling, and regenerative response.
Angiogenesis

Use in models associated with vascular support cells, pericytes, and stabilization of new vessels.
Biomaterials and Scaffolds

Evaluation of controlled release, cell adhesion, and functional response in experimental matrices.

REQUEST YOUR SAMPLE

Tell us about your experimental model and we will guide you on availability, conditions of use, and evaluation of PDGF-B MegaProt.

1

Contact Us

Complete the Beta sample request form.

2

Evaluation

We review your research profile and intended use.

3

Delivery

We ship the sample with an included usage protocol.

4

Feedback

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